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Calchaqui Valleys

Calchaqui Valleys

The complete Route 40 circuit — Cachi, Molinos, Quebrada de las Flechas & Cafayate wineries

Last updated: April 2026

The Calchaqui Valleys form one of the most spectacular road-trip circuits in South America: a loop from Salta through Cachi, Seclantes, Molinos, Angastaco, the Quebrada de las Flechas, San Carlos and Cafayate, returning to Salta via Route 68 through the Quebrada de las Conchas. The outbound route crosses the Cuesta del Obispo (3,348m), Los Cardones National Park and the Recta del Tin Tin before descending to Cachi. From Cachi, the legendary Route 40 heads south through adobe villages, ancient looms, colonial churches and the world's highest vineyards. The return via Route 68 passes through sandstone canyons sculpted by millions of years of erosion. Total distance: approximately 520 km, of which 300 km are gravel (RP 33 and Route 40). Minimum: 3 days/2 nights. Ideal: 4-5 days for a relaxed pace.

Locally verified content
Vista panorámica de la ciudad de Salta desde el Cerro San Bernardo
Cerro de los Siete Colores en Purmamarca, Quebrada de Humahuaca
Tren a las Nubes cruzando el Viaducto La Polvorilla a 4.220 m
Viñedos de altura en Cafayate con la Cordillera de los Andes

Getting there — distances & times

From Distance Flight Bus Drive
Buenos Aires (EZE) 1500 km 2 h 20 20–22 h 15–17 h
New York (JFK) 9400 km 12 h + 2 h 20 layover
Madrid (MAD) 11300 km 14 h + 2 h 20 layover
São Paulo (GRU) 2800 km 4 h 30
Córdoba 890 km 1 h 30 11–13 h 9–10 h
Mendoza 1200 km 2 h 17–19 h 13–15 h

Month-by-month climate

Month Temp. Rain Crowds Note
Jan 16° / 28°C 180 mm Rainy summer
Feb 15° / 27°C 155 mm
Mar 14° / 26°C 110 mm
Apr 11° / 24°C 30 mm Dry season starts
May 8° / 22°C 8 mm
Jun 5° / 20°C 3 mm
Jul 4° / 20°C 3 mm Winter break
Aug 6° / 22°C 5 mm
Sep 9° / 25°C 10 mm Clear skies
Oct 12° / 27°C 25 mm
Nov 14° / 28°C 60 mm
Dec 16° / 28°C 140 mm Holidays

Typical prices by category

CategoryBudgetMid-rangeLuxury
Hotel/nightUSD 15–25USD 50–90USD 150–350
Food/dayUSD 12–18USD 25–40USD 60–120
Day tourUSD 40–55USD 60–90USD 120–200
Car rental/dayUSD 30–45USD 50–70USD 90–150

Approximate ranges in USD as of April 2026. May vary with Argentine peso exchange rate.

The Route Day by Day

Day 1: Salta to Cachi via Cuesta del Obispo

Depart Salta early on RP 33. Cross the Quebrada de Escoipe (subtropical canyon), climb the Cuesta del Obispo to 3,348m, traverse Los Cardones National Park (giant cacti, Valle Encantado) and drive the Recta del Tin Tin (18 km perfectly straight). Arrive in Cachi by late afternoon. Explore the village, church, museum. Overnight in Cachi.

Day 2: Cachi to Cafayate via Route 40

The wildest day. Route 40 south through Seclantes (poncho artisans), Molinos (governor's mummy, Bodega Colome if time allows), Angastaco and the Quebrada de las Flechas (tilted rock formations). 160 km, 5 hours. Arrive in Cafayate at sunset for Torrontes on the plaza.

Day 3: Cafayate + Route 68 to Salta

Morning winery visits (Nanni, Piattelli, El Esteco). Wine ice cream at Miranda. Return to Salta via Route 68 with stops at every Quebrada de las Conchas formation: Devil's Throat, Amphitheater, Obelisk, Castles.

Key Stops Along the Route

Practical Tips

Book Your Circuit

Calchaqui Valleys 3-Day Tour

Salta-Cachi-Route 40-Cafayate-Salta. Transport, guide, 2 nights accommodation.

From USD 250
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GetYourGuide

Cachi Day Trip

Full day from Salta: Cuesta del Obispo, Los Cardones, Cachi. Bilingual guide.

From USD 45
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GetYourGuide

Cafayate Wine Tour

Route 68 canyon drive, 2 winery tastings, Cafayate. Full day from Salta.

From USD 42
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GetYourGuide

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